10. Simultaneous 19F–1H medium resolution NMR spectroscopy for online reaction monitoring

Nicolai Zientek, Clément Laurain, Klas Meyer, Matthias Kraume, Gisela Guthausen, Michael Maiwald, Journal of Magnetic Resonance, (2014), 249, 53–62 DOI: 10.1016/j.jmr.2014.10.007

Medium resolution nuclear magnetic resonance (MR-NMR) spectroscopy is currently a fast developing field, which has an enormous potential to become an important analytical tool for reaction monitoring, in hyphenated techniques, and for systematic investigations of complex mixtures. The recent developments of innovative MR-NMR spectrometers are therefore remarkable due to their possible applications in quality control, education, and process monitoring. MR-NMR spectroscopy can beneficially be applied for fast, non-invasive, and volume integrating analyses under rough environmental conditions.