Articles

A chemist´s dream to have a fast and reliable analytical tool that does not require tedious sample preparation and is available within the lab for reaction analysis might have come true with the implementation of efficient solvent suppression methods on mobile benchtop NMR spectrometers. As these instruments use compact permanent magnets, they do not require …

Lifting the curtain of undesired solvent signals – How solvent suppression and 13C decoupling remove the signals of regular protonated solvents from 1H NMR spectra to eliminate sample work-up before analysis. Read More »

Thanksgiving is just around the corner in the US, with the anticipated meal and the nap that follows. There have been several debates from where the sleepiness comes from after the Thanksgiving feast. Is it the copious amount of food, the warm-and-fuzzy feeling from being around families and friends, or the star-of-the-dinner-show turkey? There is …

From the Thanksgiving Table to Dreamland Read More »

The quantification of the ingredients of a complex formulation by NMR spectroscopy is sometimes limited by the overlapping of the signals of the multiple compounds present in the product. The situation is particularly complicated when the sample contains molecules with high molecular weight. Macromolecules have broad resonances that cover large fractions of the spectrum and …

Unmask the NMR spectra of small molecules in complex formulations Read More »

Typically, NMR samples are dissolved in deuterated solvents to avoid the overlapping of the large solvent peaks with the signal of the analytes. However, if samples need to be analyzed while they are being synthesized or if the components of a liquid formulation need to be quantified the use of deuterated solvents is not an …

NMR spectroscopy with protonated solvents as if you were using deuterated solvents Read More »

Figure 1. Spinsolve NMR spectrometer used in the chemistry lab for quick analysis of products. The typical presence of protonated solvents in the sample requires the use of solvent suppression and carbon decoupling methods to acquire the spectra of analytes of interest. NMR spectroscopy in the chemistry lab Benchtop NMR spectrometers have been developed to …

Solvent suppression: the key to measure your samples every time you need while they are synthesized Read More »

Essential oils are mixtures of volatile chemical compounds typically extracted from natural raw materials of plant origin. They consist of terpenes/terpenoid derivatives and phenolic compounds generally obtained by distillation or direct mechanical processing [1]. The term “essential” refers to the oil being the “essence of” the plant’s fragrance, but it can also indicate that the …

Identification and quality assessment of Essential oils by benchtop NMR Read More »

Small footprint mobile NMR spectrometers, like the Spinsolve, able to acquire high resolution NMR spectra with negligible operating costs are widely expanding the application field of NMR spectroscopy. The mentioned characteristics of the benchtop NMR system are demanded by applications in forensics science, where it is often highly desirable to carry out compound identification in …

Identifying hazardous and illicit compounds by benchtop NMR spectroscopy Read More »

13C spectrum of a mixture of 13 hydrocarbon molecules acquired on a Spinsolve 80 MHz. NMR is a powerful analytical method widely used to quantify the concentration of chemical compounds present in a sample. Compared to other techniques, NMR offers a number of advantages. The integral of the signals in the NMR spectrum is directly …

Quantification of single components in complex mixtures by 13C NMR Read More »

Carrier solvents are used to add flavours and aromas to a variety of different foods and drinks. Since they are not considered additives, producers are not required by law to declare them on the ingredients label. Two commonly used carrier solvents are ethanol and propylene glycol (Figure 1) which are used to dissolve the flavour …

Carrier solvents in soft and energy drinks Read More »