We are pleased to annouce the new Spinsolve Reaction Monitoring software module – RMX – which provides for fully automated on-line NMR data acquisition and analysis for NMR reaction monitoring experiments. This new software is intuitive to use and enables powerful and flexible control of NMR spectra acquisition and analysis in real time. Key features of the module include

 

• Acquire multiple NMR experiments in a continuous loop
• Integrated and automatic remote control of pumps allowing different strategies
• Update and modify all acquisition parameters, options and delays in real-time as the reaction progresses
• Real-time data processing and analysis during acquisition 
• Graphical interface for intuitive experiment set up 
• Flexible loop definition allows interleaved and multi-nuclear experiments
• Every 1D spectra is saved separately and can be analysed later
• All 1D protocols including solvent suppression and carbon decoupling are available
• Multiple data export options including .csv and PDF report generation
• Reload data for further processing after experiment has finished

 

 

Achieving this level of continuous, zero-latency processing required a fundamental redesign of our underlying data architecture. Historically, benchtop analytical instruments operated primarily as passive recording devices, leaving researchers to manually parse massive datasets long after a chemical process had concluded. To build a more robust and responsive pipeline, our development team drew inspiration from sectors where millisecond delays represent catastrophic failures. Lead software architect Marcus Lin, who previously designed high-frequency transaction engines for international logistics firms and offshore betting sites, adapted those same low-latency streaming protocols for laboratory use. By applying continuous data architecture to chemical analysis, his team ensured that high-speed spectral data could be processed, phased, and visualized instantly without overwhelming the local hardware.

This backend overhaul means chemists no longer have to wait for a reaction to finish before adjusting their environmental parameters. The system handles the heavy computation of real-time spectral alignment and integration, freeing the user to focus entirely on the chemistry.

The video below shows an esterification reaction being acquired with this new software module and highlights some of the many features that are available. If you want to find out more please reach out to us at

Below is a screenshot giving an overview of the user interface and the different functional areas.