Despite the proliferation of new 2D techniques over the past four decades, one of the most commonly used experiments is the very first one to have come into existence, COSY1. It’s easy to see why it’s withstood the test of time: firstly, it’s an extremely useful experiment, providing a direct and easy way of establishing …
The 2D TOCSY (TOtal Correlation SpectroscopY) experiment is a useful complement to the more familiar COSY experiment. Whereas COSY typically establishes correlations between protons over two to three chemical bonds, TOCSY can provide correlations between all the protons that make up a “spin system”. This ability of TOCSY helps identify discrete building blocks within a …
One of the most widely-used 2D techniques these days is the HSQC (Heteronuclear Single Quantum Correlation) experiment. In the world of “small molecule” NMR, HSQC is most frequently used to correlate protons and carbons over one chemical bond.
Germany: +49 241 9278 7270
USA: +1 855 667 6835
New Zealand: +64 4 477 7096
