Paul works as Product Support Manager for Magritek. He is currently based in San Francisco, California. He obtained his Ph.D. in NMR technique development from The University of Manchester, U.K., under the supervision of Prof. Gareth Morris.

Proton 1D mixture

The 1D TOCSY Experiment

In my last post I showed how the 2D TOCSY experiment can be used to identify individual “spin systems” or subunits within a molecule, or even within different molecules. Well, there is a very closely related, one-dimensional version of the TOCSY experiment that uses something called “selective excitation” in place of a full 2D experiment. …

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The 2D TOCSY Experiment

The 2D TOCSY (TOtal Correlation SpectroscopY) experiment is a useful complement to the more familiar COSY experiment. Whereas COSY typically establishes correlations between protons over two to three chemical bonds, TOCSY can provide correlations between all the protons that make up a “spin system”. This ability of TOCSY helps identify discrete building blocks within a …

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