Quantifying the formation of stereoisomers on-line during an HWE reaction employing benchtop NMR spectroscopy
The on-line monitoring of chemical reactions employing NMR spectroscopy provides a deeper insight into the kinetics of the reaction in question and its mechanism. Several nuclei like 1H, 19F or 31P can be detected exclusively or combined in a consecutive experiment loop to follow the course of the reaction and to identify and quantify the …