Silicon NMR is a powerful analytical method used to characterize various types of materials. The NMR-active isotope is 29Si and silicon signals of different chemical groups spread over a wide chemical shift range. In this case study we utilize the high sensitivity of silicon to the surrounding atoms to confirm the composition of polysiloxanes. The …
Silicon NMR on Spinsolve benchtop NMR spectrometers Read More »
While for small molecules standard 1D proton measurements are mostly sufficient to do a full structural assignment, larger molecules often require the information from additional homo- and hetero- nuclear correlation experiments for an unambiguous assignment. As for such molecules often only a limited amount of substance is available it is important that the NMR-spectrometer provides …
Structure verification of Brucine by advanced homo and heteronuclear NMR. Read More »
SPHOS (2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) is a widely used air-stable phosphine ligand employed together with e.g palladium in a range of different catalytic reactions. Figure 1 shows the 1H NMR spectrum of a 800 mM SPHOS sample in CDCl3 measured in a single scan taking 15 seconds to acquire. Figure 1: 1H NMR spectrum of a 800 …
1H Spectra 5-Bromo-1,2,3-trifluorobenzene (BrC6H2F3) is a structurally simple molecule commonly used as a building block in a variety of synthetic organic reactions. As this molecule contains 1H, 19F, and 13C (in natural abundance), it is a beautiful example to demonstrate the unique advantage offered by the Spinsolve of accessing all three nuclei simultaneously without requiring …
Paliperidone is the essential metabolite of risperidone, an atypical antipsychotic employed for the treatments of schizophrenia or bipolar disorders. Its chemical structure consists of a benzisoxazole moiety and it is less lipophilic than risperidone. Being an example of atypical antipsychotics, it acts more as a serotonin-receptor blocker than a dopamine-receptor one. The interested reader is …
In a previous application note we described the advantages and prerequisites for performing qNMR with an internal standard. However, this method is not easy to implement on samples taken directly from the production line. In this case, the main complication comes from the fact that the type of sample preparation required to add an internal …
Ethylene Propylene Diene Monomer (EPDM) is a synthetic terpolymer rubber prepared from ethylene, propylene, and non-conjugated diene monomers that are incorporated in the polymer chain to enable crosslinking via vulcanization. After polymerization and purification, free diene monomer can remain in the copolymer. Detection and quantification of this monomer is important as it impacts the vulcanization …
The Spinsolve Ultra benchtop NMR spectrometer can be easily used to look at some of the main components in milk, like water, fat, and lactose. Milk contains around 87% of water, therefore the water signal dominates the spectrum and overlaps with the signal of some of the other components in the sample. Running a PRESAT …
Determination of lactose, fat and water content in milk Read More »
Join Magritek at the virtual CDT 2021 Symposium on March 15th to 17th. The Chemiedozententagung (CDT) is a symposium that brings together young academics from all areas of chemistry. Post-doctoral candidates and junior professors use this platform to present their research and to exchange ideas with future colleagues. Click here for more information
Honey is a well-known natural food source, made by bees using nectar from flowers. Typically honey is classified by color and flavor depending on the type of flower from which the nectar was harvested from. Pure honey is a complex supersaturated solution containing 80% sugars and unique combination of chemical compounds such as phenolic, flavonoids, …
Identification and quantification of methylglyoxal in Manuka honey Read More »
Germany: +49 241 9278 7270
USA: +1 855 667 6835
New Zealand: +64 4 477 7096
